The most reliable and accurate transthoracic acoustic widow to assess catheter position is the parasternal long-axis window because it will provide a view of the catheter from an orthogonal angle of insonation (Figure 4). We have 2 nurses at the bedside for the tubing change. Impella use in real-world cardiogenic shock patients: Sobering outcomes. She was taken to the catheterization laboratory, where she was found to have a significant obstruction of the left main coronary artery complicated by plaque rupture. Your message has been successfully sent to your colleague. All cases are also followed by the cardiac surgeon who oversees our VAD program and a critical care intensivist. The second indication is to prevent clot formation on the catheter itself and potential embolization into the patient. The console can run on a fully charged battery for up to 1 hour. If hemolysis is suspected, Jess offers the following troubleshooting tips: Address and correct any active position or suction alarms to help prevent hemolysis. In these illustrations, the Impella Catheter is positioned correctly. High-risk PCI - Impella 2.5, CP - < 6 hours (temporary) VAD for use during high-risk percutaneous coronary intervention (prevent hemodynamic instability) 2. We review Impella and other percutaneous devices such as intra-aortic balloon pump, TandemHeart, and extracorporeal membrane oxygenation (ECMO) and the evidence supporting their use in the setting of CS. Background and aim This study aimed to assess right ventricular (RV) function during cardiogenic shock due to acute left ventricular (LV) failure, including during LV unloading with Impella CP and an added moderate dose of norepinephrine. Hemodynamically, we typically titrate fluid balance goals and inotropes to target a right atrial pressure of 812 mm Hg and a pulmonary artery pulsatility index >1. When the physician is ready to discontinue the Impella 2.5 catheter, the groin dressing should be removed, the site cleansed with chloroprep, and the sutures clipped. Fluoroscopic image of Impella 2.5 in place in the aorta. E-mail: [emailprotected]; Twitter: @AlexPapolos. 2. position is wrong. Four hours later, after the activated clotting time was less than 150 seconds, the venous and arterial sheaths were removed and hemostasis was achieved after 40 minutes of manual compression. Usefulness of Impella support in different clinical settings in cardiogenic shock. 2020 Jul;8(13):835. doi: 10.21037/atm.2020.03.152. A 71-year-old man was referred to our facility for saphenous vein bypass graft (SVG), a high-risk PCI. Expert Rev Med Devices. In these situations, one must weigh the risk of time-dependent device-related complications with inotrope-related increases in myocardial oxygen demands. All had poor ventricular function (ejection fraction =35%) and had PCI on an unprotected left main coronary artery or the last remaining patent coronary artery or graft. Catheters with SmartAssist have an upgraded optical pressure sensor that directly measures aortic pressure and uses changes in motor current to infer an estimated LV pressure waveform. By continuing to use our website, you are agreeing to our, http://bmctoday.net/citoday/2009/09/supplement/article.asp?f=0909_supp_01.php, https://doi.org/10.1016/j.ijcard.2009.08.003, Potential Complications of Impella Therapy, Nursing Care of Patients With an Impella 2.5 for Circulatory Support, Copyright 2023 American Association of Critical-Care Nurses. The motor current will be flattened. Cardiogenic shock (CS) is a life-threatening condition associated with significant morbidity and mortality. He was discharged home 2 days later. If Impella malposition is suspected, use echo to look for inlet or outlet obstructions. SmartAssist technology on the Impella CP or Impella 5.5 devices can help with this as well. We follow our hospitals protocol for achieving hemostasis, using either manual or mechanical compression. The heparinized saline is placed in a pressure bag that is inflated to 300 mm Hg. b)x""o0``k1h^xyW While the inability to provide anticoagulation is a contraindication, there is ongoing research into nonanticoagulant purge solution alternatives. An SvO2 pulmonary artery catheter showed that the patients baseline pulmonary artery pressures were markedly elevated at 69/4047 mm Hg (normal: 2030/812 mm Hg; mean, 25 mm Hg). Coordination with the perfusionist is essential when patients are being placed on cardiopulmonary bypass. With the Impella continuing at maximum flow of 2.5 L, 2 bare metal stents were deployed in the SVG to the posterior lateral branch. Furthermore, crowding of the inlet or outlet areas increases shear stress on the red blood cells pumped through the cannula, accelerating the rate of hemolysis caused by the device. The cannula portion of the catheter is built with a 30 bend (except for the Impella LD, which has a straight design). Two patients had transient hemolysis that was not clinically significant. However, in our experience, measuring structures that can be directly visualized with ultrasound is a more practical and reproducible strategy, and thus we recommend measuring from the aortic annulus to the end of the railroad tracks. Cardiogenic shock - Impella 2.5, CP, 5.0, LD - Temporary VAD for less than or equal to 4 days: 2.5, CP - Temporary VAD for less than or equal to 14 dyas: 5.0, LD : Anticoagulation of, 4. SyBbhD&,V}R#Ohov]F}9v_c- More blood products were administered to patients treated with the Impella. The physician can evaluate left ventricular size and function and can quickly assess how well the patient tolerates decreases in the performance level. Abdullah KQA, Roedler JV, Vom Dahl J, Szendey I, Haake H, Eckardt L, Topf A, Ohnewein B, Jirak P, Motloch LJ, Wernly B, Larbig R. PLoS One. may email you for journal alerts and information, but is committed Data is temporarily unavailable. Context in source publication. The Impella 2.5 instructions for use recommend a 40-minute manual hold to achieve hemostasis at the arterial access site. Percutaneous Mechanical Circulatory Support Devices for High-Risk Percutaneous Coronary Intervention. 2 main types of pumps currently used: Additionally, cardiac resuscitation can cause device migration and as such, post-arrest ultrasound confirmation of position is recommended. Hear the stories of patients and explore the latest innovations in Impella technology. As the performance level increases, the flow rate and number of revolutions per minute increase. and transmitted securely. 0000014939 00000 n There are two indications for anticoagulation when using the Impella catheter. If the catheter is completely out of the ventricle, it should be repositioned across the valve over a guidewire. Further to this point, cases of Impella weaning intolerance or clinical decompensation after explantation beg the complicated question of when to consider escalating inotropes and/or pursuing additional MCS as bridge-to-recovery or bridge-to-LVAD/transplant versus palliation, and must be determined on an individual basis. P2 is the lowest performance level that can be used while the distal end of the Impella 2.5 is in the left ventricle. Even a common cold can cause your uvula to swell. To date, we have placed an Impella 2.5 in about 40 patients. Our training for staff from the catheterization laboratory consisted of a 3-hour session with didactic and hands-on training. He was evaluated by our cardiothoracic surgery team and was deemed an extremely poor candidate for surgery. The Impella (Abiomed Inc.) is an axial flow pump on a pigtail catheter that is placed across the aortic valve to unload the left ventricle by delivering non-pulsatile blood flow to the ascending aorta. Rotation can often be difficult and applying more than a full 360 degrees of torque is often necessary. Staff received 1-to-1 mentoring from the Impella coordinator. Signs of pulmonary congestion should be monitored, as, at least in theory, high Impella RP support with reduced LV function could cause overflow and pulmonary congestion. Unable to load your collection due to an error, Unable to load your delegates due to an error. 0000007230 00000 n 0000006172 00000 n We have also placed the Impella 5.0 in 3 patients. When activated, the console is silent. Placement monitoring screen display shows that pump position is wrong. He had a history of coronary artery bypass grafting surgery several years prior as well as heart failure. 1. If TTE imaging is difficult, fluoroscopy or TEE can also be used. Additionally, patients are observed by the VAD coordinator. Our practice is to integrate clinical factors, such as mean arterial pressure, heart rate, and urine output with invasive hemodynamics, and lab dataspecifically, serum lactate and pulmonary arterial oxygen saturation every 6 hours. The Impella 2.5 cannot be used on all acutely ill patients who require hemodynamic support.14 Because the device is designed to sit across the aortic valve in the left ventricle, it should not be used in patients who have prosthetic aortic valves, so as to prevent damage to the valve. The Impella (Abiomed, Danvers, MA) mechanical circulatory support (MCS) system is a catheter-based continuous flow pump that is typically placed percutaneously or by surgical cutdown into the femoral or subclavian artery. Careers. There is a pressure sensor built into the aortic end of the cannula that is used to produce a placement signal waveform tracing (Figure 3A). The power connections for the pump motor and sensors are . The symptoms usually last about four to seven days and don't typically require a trip to the healthcare provider, unless it affects an infant or if complications develop. A patient experiencing continuous suction may show systolic LV numbers, shown in white, that are uncoupled from the aortic numbers shown in red. The placement signal will show a normal appearing aortic waveform with systolic and diastolic pressures similar to those shown by the patients arterial catheter. The performance level determines the flow rate and the number of revolutions per minute. The proximal port of this lumen is red. Expert commentary: Based on our experiences, we share the following recommendations. Accessibility Cardiogenic shock complicates 5-10% of cases of myocardial infarction 1-3 and mechanical support devices have demonstrated limited benefit with early initiation and appropriate protocols. Train a core group of nurses and cardiovascular technologists from the catheterization laboratory for initial setup of the console, catheter preparation, and assisting with placement of the device. At the end of the procedure, she was symptom free, and she was rapidly weaned from the Impella and the device was removed. The device received 510(k) clearance from the Food and Drug Administration in June 2008 for providing up to 6 hours of partial circulatory support. Ann Transl Med. It is a single tubing system that bifurcates and connects to each port of the catheter. Garan AR, Kanwar M, Thayer KL, et al. The patient was weaned from the Impella device, the device was removed in the catheterization laboratory, and the venous and arterial sheaths were secured in place.
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